INHIBITION OF SYNTHESIS OF SULFATED MUCOPOLYSACCHARIDES BY ESTRADIOL
نویسندگان
چکیده
منابع مشابه
Inhibition of Synthesis of Sulfated Mucopolysaccharides by Estradiol
The influence of estradiol upon incorporation of isotopes into the sulfated acid mucopolysaccharides of connective tissues of the rat has been studied. Administration of the hormone for 3 weeks significantly reduces the in vitro incorporation of S(35)-sulfate into cartilage and thoracic aorta without significantly altering the amount of hydrolyzable sulfate in these tissues. The reduction of su...
متن کاملThe effect of dibutyryl cyclic adenosine monophosphate on synthesis of sulfated acid mucopolysaccharides by transformed fibroblasts.
The effect of dibutyryl-cyclic adenosine 3’,5’-monophosphate and theophylline on the incorporation of [%]sulfate into acid mucopolysaccharides by 3T3 and SV3T3 fibroblasts has been studied. SV40 transformation of 3T3 fibroblasts produced a marked decrease in the rate of synthesis of acid mucopolysaccharides, in agreement with the data of others. When the transformed cells were grown in medium s...
متن کاملDistribution of sulfated mucopolysaccharides in invertebrates.
The sulfated mucopolysaccharide composition of 22 species of invertebrates belonging to the phyla Arthropoda, Mollusca, Annelida, Tunicata, Echinodermata, Coelenterata, and Porifera was analyzed. It is shown that all the species contain variable amounts of one or more types of sulfated mocopolysaccharides, most of which similar to the ones found in vertebrates. It is shown also that each specie...
متن کاملThe Sulfated Mucopolysaccharides Human Umbilical Cord*
Umbilical cord was shown to contain chondroitin sulfate B and a small amount of glucosamine-containing sulfated mucopolysaccharide, in addition to hyaluronic acid and chondroitin sulfate C. All of the hyaluronic acid and part of the chondroitin sulfate C could be extracted directly with dilute sodium chloride; the rest of the chondroitin sulfate C and the chondroitin sulfate B were released onl...
متن کاملDistribution and synthesis of sulfated mucopolysaccharides in the retina of the rat
The distribution and synthesis of retinal mucopolysaccharides (MPS) in the rat have been studied by autoradiography, following injection of S-sulfate, supplemented by histochemical procedures. The results indicate that sulfated MPS occur in the plexiform and optic nerve fiber layers, but are most heavily concentrated in the photoreceptor zone. In this zone, production of MPS becomes significant...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1962
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.116.4.565